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Chronic stress and poor sleep elevate cortisol chronically, which can partially counteract the appetite-suppressing effects of GLP-1 therapy
Food and Drug Adminstration
This pre-specified analysis of the SURPASS-CVOT randomised clinical trial evaluates the comparative effects of once-weekly tirzepatide versus dulaglutide on heart failure outcomes in patients with type 2 diabetes, established atherosclerotic cardiovascular disease (ASCVD), and prior heart failure
Glossitis (inflamed tongue) usually resolves within two to three weeks, and patients report reduced oral discomfort
Heres how the oral vs injectable options break down: Injectable The most effective drugs (measured by weight loss in clinical trials) are weekly injections, including Wegovy, Ozempic, Mounjaro, and Zepbound