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Multiple randomized analyses show GLP-1sespecially semaglutideproduce meaningful hs-CRP reductions : STEP 1/2/3 (weight-management trials): Semaglutide 2.4 mg weekly reduced CRP by ~3944% vs

At the same time, semaglutide decreases the release of glucagon

And these investigators found improvements in pretty much not every single hallmark of aging, but I think seven of the nine different hallmarks of aging, including telomere stability, epigenetic stability, as well as mitochondrial function, proteostasis

For example, after we have not eaten for several hours, GSH production in many of our cells slows considerably

Long-term effects unknown: The longest published exposures are months-long rodent studies

Supplements We recommend discussing vitamin B12 and/or folate supplements with a health care professional before starting supplementation