Preserving muscle mass is essential for maintaining strength, mobility, and overall physical function
It is still in clinical trials but has generated significant interest due to exceptional weight loss results in early studies
Further, data on GLP-1 usage is limited internationally, and examining the global landscape for these drugs primarily highlights the scarcity of pediatric specific evidence and guidelines across countries
WARNINGS Hypersensitivity Reactions Serious hypersensitivity reactions, including anaphylaxis, laryngeal edema, and bronchospasm have been reported following levocarnitine administration, mostly in patients with end-stage renal disease (ESRD) who are undergoing dialysis
For instance, short-acting GLP-1RAs are more strongly associated with delayed gastric emptying than long-acting agents, leading to a greater impact on postprandial glucose
Gold SL, Manning L, Kohler D, Ungaro R, Sands B, Raman M