4 mg of retatrutide A Clinician's Guide to Dosing Retatrutide Dosing Guide: 2mg–12mg Protocol

Wegovy has a well-documented safety profile supported by years of clinical use in the UK

Compounded medications are made by third parties that have access to the medically active molecule

Check at baseline, 6-8 weeks after starting, after each 10-15 pounds of weight loss, every 3-4 months during active weight loss, and every 6 months after weight stabilization

Agonist-modulated palmitoylation of endothelial nitric oxide synthase

People with high insulin resistance (ie, people with obesity), young age at dysglycaemia, abnormal 1 h glucose concentrations (86 mmol/L) despite normal 2 hr glucose concentrations on 75 g oral glucose tolerance test, and low C-peptide are at higher risk for progressing to stage 3 (fast progressor, stage 2b) than those diagnosed with dysglycaemia after age 65 years (slow progressor, stage 2a)

So we dont have definitive evidence to compare them directly