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Allergic reactions to proprietary preparations of vitamin B12 might be due to substances added to the solutions as preservatives or for other reasons, to impurities from the production, or to the vitamin B12 itself

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After incubation, the samples were washed three times with PBS to remove excess reaction solution

According to the SmPC, Rybelsus should be discontinued if pancreatitis is suspected and should not be restarted if pancreatitis is confirmed

Long-term reliability of pressure algometry in healthy volunteers