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Potential Risks and Side Effects of Synthetic HGH The Endocrine Society notes several concerns with synthetic HGH therapy, particularly when used for anti-aging purposes rather than true medical deficiency: Fluid retention and edema (swelling in hands and feet) Joint pain and muscle aches Carpal tunnel syndrome Increased insulin resistance and potential diabetes risk Gynecomastia (enlarged breast tissue in men) Potential acceleration of existing cancers (though not proven to cause cancer) Suppression of natural pituitary function These side effects typically occur because synthetic HGH provides constant, unregulated hormone levels rather than the natural pulsatile (rhythmic) secretion your body is designed to produce

This creates a vicious cycle where metabolic dysfunction perpetuates further insulin resistance

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In some rare cases, patients can develop a painful condition called acute pancreatitis

Tim Nicaise grew up competing in gymnastics, which helped him maintain a weight of about 140 pounds for most of his life

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