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doi: 10.1038/s41418-021-00859-z 23 ChenXYuCKangRKroemerGTangD

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ICC are responsible for multiple functions in the GI tract

PT-141 binds to melanocortin receptors in the brain, stimulating areas that affect sexual arousal

Phase 2 trial data showed a mean body weight reduction of approximately 24% at the highest dose (12 mg) over 48 weeks, though Phase 3 confirmation is required

Moreover, individuals who are malnourished, have cancer, are elderly, pregnant, or are alcoholics are also at higher risk in suffering the lack of vitamin B12