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The flagship trial STEP-1 (published in NEJM , 2021) found a mean weight reduction of ~14.9% of body weight with semaglutide 2.4 mg vs ~2.4% with placebo over 68 weeks ( [12] )
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What does it mean to microdose GLP-1s
Green Tea Extract animal and small human studies show GLP-1 stimulation
FOXO4-DRI is reported to be sensitive to oxidation and repeated freeze-thaw cycles, so reconstituted material is best used fresh rather than stored for months
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