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Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine 24(4):564573 Kassubek J, Unrath A, Huppertz HJ, Lul D, Ethofer T, Sperfeld AD, Ludolph AC (2005) Global brain atrophy and corticospinal tract alterations in ALS, as investigated by voxel-based morphometry of 3-D MRI