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[36, 37] Unlike conventional hypodermic needles, microneedle systems create transient microchannels that bypass the stratum corneum, enabling efficient transdermal transport of a wide range of molecules, including peptides, proteins, and small drugs, without reaching nerve-rich deeper layers and thus minimizing pain and risk of infection [38, 39]

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Although approximately 1 in 1500 patients exhibit signs of chronic liver injury in long-term prophylactic therapy, acute liver injury due to NFT is quite rare, with approximately 0.3 cases per 100,000 prescriptions (LiverTox 2020)

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By combining a short-acting GHRH fragment with a selective ghrelin-pathway peptide, this formulation supports controlled investigation of complementary peptide interactions

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Herpes simplex virus infections (Fig

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