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The FLOW trial also highlights the renal protective effects of GLP-1RAs, suggesting a close link between renal and cardiovascular benefits, which warrants further mechanistic studies (256)
To explore the mechanism by which pasireotide acts on intestinal L-cells, we investigated the impact of DCA, or a nutrient mimicking our daily meals, on GLP-1 secretion from GLUTag cells
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Then, the mice were imaged with 10-min static PET scanning
These studies have contributed to understanding the potential role of NNMT in metabolic disorders
The half-life is too long
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