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If you've spent any time researching regenerative medicine, anti-aging peptides, or the quiet boom in "longevity skincare," one three-letter code keeps surfacing: GHK-Cu
Since detoxification pathways can be blocked in individuals with gut and autoimmune issues due to certain genetics and SNPs, it is important to boost glutathione to support these pathways, our DNA, and cells so the body is eliminating the toxins that can accumulate and contribute to leaky gut (or make it worse)
Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action As a copper chelator, GHK-Cu modulates over 4,000 human genes, upregulating those involved in tissue remodeling (e.g., collagen I, III) and downregulating pro-inflammatory pathways like NF-B
Always check with a health-care professional on the interactions
When copper ions are too reactive, they can cause oxidation of other ingredients or irritate skin
WIRES Nanomed Nanobi 9 (2), e1410
