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5 Semaglutide Treatment 6 Who is a Candidate for Semaglutide
The companys stock has fallen about 58% over the past year as In 2023, the American Society of Anesthesiologists (ASA) issued guidelines advising patients to discontinue GLP-1 receptor agonists (GLP1-RAs) a week before surgery, citing concerns over potential operative complications, leading to delayed or rescheduled surgeries across the U.S
Both medications may support weight loss under medical supervision, but they work slightly differently
But there have also been concerns about safety
Animal studies suggest GLP-1 signaling in the brain may help recalibrate sleep-wake cycles entirely independent of body weight changes, though these findings have not yet been replicated in humans (ref)
Evidence layer: GLP-1 food-record studies, glucagon/carb mechanism, micronutrient gaps, and sample-day targets sit under the operational how-to
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