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The enzyme aromatase, present in fat cells, converts androgens to oestrogensa process that becomes increasingly important after menopause when ovarian oestrogen production declines

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That crossover keeps the category culturally aspirational even as it becomes medically mainstream

When cells become less sensitive to insulin, the body is more likely to store glucose as fat rather than using it for immediate energy

doi: 10.1007/s00394-013-0511-0 75