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Metabolic shift in hypoxia-adapted CML cells and mechanisms of acquired dasatinib resistance uncovered by proteomic iTRAQ profiling

323,324 Lactate-derived lactylation is consequently involved in modulating inflammation in RA

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In addition to genetic factors, immunological-inflammatory factors, oxidative stress, and disturbances in neurotransmitter metabolism, kynurenine and serotonin pathways may play a role

The peptide also inhibits 5-alpha reductase, the enzyme that converts testosterone to DHT, potentially reducing follicular miniaturization

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