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doi: 10.1002/14651858.CD012990.pub2 84
Functional groups: While both compounds possess functional groups that contribute to their activity, the specific types and arrangements differ significantly
Patients Who've Failed Lifestyle Intervention: Sustained caloric restriction fails the majority of people who attempt it long-term not because of inadequate motivation, but because the hypothalamic weight-defense mechanisms that evolved to protect against starvation actively counteract weight loss, increasing appetite and reducing metabolic rate in response to caloric deficit
Clerte, M
