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The core mechanism of action of IGF-1 LR3 IGF-1 LR3 activates downstream signaling pathways (such as the AKT/mTOR pathway) by binding to the IGF-1 receptor (IGF1R) on the cell surface, regulating cell proliferation, differentiation, migration, and metabolism
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doi: 10.1038/s41598-020-64464-9 101
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The reason lies in its alignment with the bodys endogenous GH rhythm
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