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investigational potentials

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Adverse reactions so far reported with these drugs include pancreatic insufficiency (Gier et al., 2012), gallstones (Rehfeld et al., 2018), gastroparesis (Sodhi et al., 2023), non-arteritic anterior ischemic optic neuropathy - NAION (Hathaway et al., 2024) and increase in diabetic retinopathy (Bain et al., 2018)

The trial portfolio included three single-dose pharmacokinetic studies and three multiple-dose efficacy trials

Diabetic wound models have also been studied, given the clinical relevance of impaired healing in metabolic disease

For selected patients, obesity treatment may involve more than one tool rather than a choice of medication or procedure alone