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SIRT1 Activation: Promotes fat oxidation, muscle preservation, and reduced inflammation (Price et al., Cell Metabolism )

This is in part due to the fact that the amino acids glutamate and proline can easily substitute for many of the metabolic roles of glutamine, including energy production and amino acid synthesis

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5 In vitro organ protection effects of ISO The in vitro antitumor activities of ISO are described in detail above (Table 4), while the potential in vitro organ protective effects of ISO are reviewed in the following sections