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If reflux has been managed with medication, attempt a gradual step-down after 4 to 6 weeks at maintenance
Taylor starts low, goes slow, and adjusts your plan to keep you comfortable
2013;5(209):209ra151
Orforglipron, developed by Eli Lilly, is the first non-peptide oral GLP-1 agonist, achieving up to 1.8% HbA1c reduction and 1012% body-weight loss in Phase 3 trials
When used with insulin or sulfonylureas, these medications may increase hypoglycemia risk, requiring dose adjustments of those agents
There was no significant difference in acute cardiovascular events
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