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PLoS One 7, e49677

AKG supplementation dramatically inhibited apoptotic cell death caused by TRAIL treatment upon inhibition of Gln metabolism under Gln deprivation conditions or BPTES treatment (Fig

Nrf2 activation promotes GSH-mediated antioxidant defense.Bottom right (Parkinsons disease): dopaminergic neurons in the substantia nigra accumulate Lewy bodies and undergo degeneration