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Here is what I actually think about GHK-Cu in perimenopause: where the data is strongest, where it is weaker, and how I think about it in my own practice
The selective sodium-glucose co-transporter 2 inhibitors (SGLT-2 inhibitors), also glucose-lowering agents, can lead to moderate effects on weight loss, examples include: canagliflozin (Invokana), empagliflozin (Jardiance), ertugliflozin (Steglatro) and dapagliflozin (Farxiga)
Do not increase your dose early because weight loss feels slow, and do not take an additional dose to make up for a missed injection unless your healthcare provider or official medication instructions tell you to do so
The result is a reduction in muscle contraction intensity, making it the primary reagent for investigating the reduction of dynamic wrinkles and expression lines
However, substantial inter-person variability exists in both weight loss efficacy and the incidence of side effects 1
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