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They form a tightly regulated signaling network with multiple overlaps in signaling pathways between distinct RCDs to ensure the most appropriate cellular response to stress factors [1]
In an oxidative ER environment, activated ERO1 generates disulfide bonds by consuming O 2 in the presence of flavin cofactors, which are then passed to the protein for folding via PDI (Wang et al., 2014)
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1 Nutritional and phytochemical profile Amla is considered one of the richest natural sources of vitamin C, as it contains 193720 mg per 100 g of fresh fruit across cultivars, which significantly exceeds vitamin C levels in apples, limes, pomegranates, and grapes
References Wang Y, You Y, Chen H, Liu J, Wu Q, Dai K et al (2024) 3D-bioprinted anti-senescence organoid scaffolds repair cartilage defect and prevent joint degeneration via miR-23b/ELOVL5-mediated metabolic rewiring
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