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These results suggest that the expression levels of core factors of the autophagy signal transduction pathway are closely related to ferroptosis and have a certain correlation with the development and prognosis of ovarian cancer
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In addition, dietary flavones promote the dissociation of NRF2 from Kelch-like ECH-associated protein 1 (Keap1) through two mechanisms: PKC-mediated phosphorylation of NRF2 and P62-mediated autophagic degradation of Keap1 [20]
Muscle Aches and Joint Pain: By downregulating the production of pro-inflammatory cytokines like IL-6 and TNF-alpha, glutathione helps mitigate the systemic inflammation that drives chronic musculoskeletal pain
