For semaglutide specifically, it's advised to stop treatment at least 2 months before a planned pregnancy
There are some people who should not use semaglutide for weight loss
Options include switching to injectable semaglutide for higher doses, adding an SGLT2 inhibitor or metformin, combining therapies, or starting insulin if needed
Phase 3: the REDEFINE trials The Phase 3 programme for CagriSema is conducted under the name REDEFINE a series of large, randomised, controlled trials designed to confirm efficacy and establish the safety profile required for regulatory approval
By practicing intermittent fasting, insulin resistance can be reduced
Leidy HJ, Clifton PM, Astrup A, et al