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Let it approach room temperature to reduce injection discomfort
Composed of 15 amino acids, researchers study it for its tissue healing properties
For in-clinic injections, experienced staff administer injections with 25 to 30 gauge needles and site rotation to prevent fibrosis
Potential model types include: Reconstructed tissue models Organoids Hydrogel systems Collagen scaffolds Decellularized matrices Co-culture models Ex vivo tissue sections Microfluidic systems Findings should remain specific to the architecture, cell composition, and analytical methods used
A convenience sample of children diagnosed with a precursor to hypermobile EDS at a tertiary hospital who were followed for three years found four factors that predicted disease severity and modestly predicted development of disability over time: multisystem involvement, pain, fatigue, and postural control
Oct 2021;142:112040
