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9 A better understanding of the link between diet, specific micro-organisms within the microbiome, and energy metabolism may yield new treatments (including probiotics) that may assist patients in managing cravings, achieving weight loss goals, reversing insulin resistance, and avoiding related disorders

DOI: 10.1371/journal.pone.0088063

The interaction of Smad7 and TGF- signaling is emerging as an important factor in pancreatic beta-cell homeostasis and formation (El-Gohary 2013)

This benefit is especially significant in older adult populations, who generally demonstrate a weaker antibody response (seroconversion) to such immunizations (514)

It is prolonged, cumulative exposure that causes measurable degradation