summit trial tirzepatide benefits obese HFpEF patients with and without type 2 diabetes SUMMIT: Tirzepatide Improves Outcomes and

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2 In participants taking tirzepatide with metformin alone (without sulfonylureas), the results at two years showed: HbA1c reductions of 2.3% to 2.6% depending on dose Very low rates of hypoglycaemia (0.9% to 3.6%) Sustained weight loss throughout the study period How do Mounjaro and metformin work together

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