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This can reflect either vasogenic or cytotoxic edema, with the latter indicated by a reduction in the ADC (apparent diffusion coefficient)

That means going through roughly 6 vials per month

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My feeling is that if you use any smaller gauge of needle you risk damaging the surrounding tissue at the injection site

riboflavin (B2), which must be converted by flavokinase Both are inexpensive supplements, so it doesnt cost a lot more to get the R5P active form