Until we have larger, more definitive studies, the safest approach is still to stop GLP-1 medications before trying to conceive. The findings, however, are exactly the kind of data we need to justify properly designed prospective trials, says Lora Shahine, MD, a reproductive endocrinologist and obstetrician-gynecologist at PNWF IVY Fertility Center in Bellevue, Washington, and host of the Brave and Curious podcast
But pre-filled pens cost significantly more than compounded vials, which is why many people turn to affordable compounded tirzepatide options and manage their own unit-based dosing
Read a HealthDay article about the study: New Study Suggests No Major Adverse Outcomes With Early GLP-1 Exposure During Pregnancy
Gallbladder Problems Semaglutide and similar medications increase the risk of gallbladder issues by about 37%
Use is contraindicated in individuals with baseline hypoglycemia or conditions predisposing to hypoglycemia
The FDA approved types of GPL-1 diabetes treatments for weight loss including versions of Mounjaro and Ozempic