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Their use is rising rapidly, and with good reason: These medications have been shown to reduce blood sugar, improve fatty liver, GERD, sleep apnea, osteoarthritis, blood pressure, triglycerides, major adverse cardiovascular events, and even show potential benefits for conditions like alcohol use disorder (Mozaffarian et al., 2025
doi: 10.1016/j.smallrumres.2025.107465 184
Along with glycemic control, it quickly became obvious that the drug also facilitated weight loss
Cho YM, Wideman RD, Kieffer TJ
Varied results have been obtained, and more robust and larger-scale RCTs are necessary to draw definitive conclusions
This recommendation reflects a paradigm shift from a glucose-centric model toward a more comprehensive cardiometabolic approach
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