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McGinnis MR, Tyring SK

The process of transamination within the body facilitates the synthesis of substantial amino acid pools, thereby contributing to the availability of essential protein sources

COX-2 selective NSAIDs (i.e., COX-2 inhibitors or coxibs) inhibit COX-2 more strongly than COX-1, resulting in less gastrointestinal side effects, but potential cardiovascular complications, most notably an increase in the risk of heart attack due to increased blood clotting propensity (see below) (Conaghan 2012)

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Typical daily range: 300500 mcg once daily (gradual titration)