Starting with a low semaglutide dose of 0.25 mg allows the body to adjust gradually, minimizing the risk of adverse effects, particularly gastrointestinal symptoms common at the beginning of treatment
hence, neither participants nor investigators were blinded to group assignments
However, clinical practitioners often recommend a "start low and go slow" approach, particularly for patients with severe chronic illness who may be highly sensitive to new supplements or prone to detoxification reactions (Herxheimer reactions)
HGH is significantly more expensive
A comprehensive approach considers diet, exercise, psychological support, and personalized treatment plans
Usually, people start with a low dose to reduce possible side effects, and then slowly increase the dose over time