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First up was Bydureon (extended-release exenatide), which used teeny-tiny biodegradable microspheres that slowly leaked the drug into your system over a whole week, like a slow-drip coffee maker for your pancreas
also measured Sirt-1related genes and reported similar results (15)
doi: 10.1038/s41420-021-00751-2 121 WuYYangRLanJWuYHuangJFanQet al
USA 79 , 345349 (1982)
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