Multiple in-vitro fibroblast studies and a smaller number of clinical-cosmetic studies report improvements in skin elasticity associated with GHK-Cu exposure, linked to increased elastin synthesis and improved lysyl-oxidase-dependent cross-linking
A larger individual may require more glutathione to reach the "excess" levels needed to impact melanin production
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Oral glutathione: goes through digestive processing follows natural absorption pathways allows the body to regulate uptake IV glutathione: bypasses digestive filtering delivers high concentrations rapidly carries greater misuse risk Most safety concerns reported publicly involve IV misuse not regulated oral supplementation