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They also play a role in other contexts, such as scarring, abnormal tissue growth and cancer biology
Referral thresholds are broadly guided by NICE but may vary according to local NHS Integrated Care System (ICS) policies
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Supplementation should always be integrated into a broader protocol that includes aggressive pacing to manage post-exertional malaise, careful symptom tracking, dietary modifications to support histamine clearance, and ongoing medical care from specialists who truly understand the interconnected nature of neuro-immune diseases
Cellular senescence, initially identified as a tumor suppressor mechanism and contributor to aging, is emerging as a potentially significant player in the pathogenesis of endometriosis