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Seek medical advice if you experience severe or persistent abdominal pain (especially radiating to your back), blood in vomit or stools, persistent vomiting, signs of dehydration, jaundice, or symptoms that worsen despite treatment, as these may indicate serious complications

doi: 10.3389/fphar.2017.00128 80 HuangL.ZhangJ

In many cases, adjustments to dosing or additional support can make treatment tolerable

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