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The exact reason is unclear, but changes in metabolism, appetite, or reduced calorie intake may contribute
These changes do not represent permanent metabolic harm but rather the expected pharmacodynamic offset
It is not a drug, food, dietary supplement, cosmetic, or medical device, has not been evaluated by the FDA, and must not be administered to, consumed by, or otherwise introduced into humans or animals under any circumstances
doi: 10.1053/j.gastro.2019.05.004 257 GengHWYinFYZhangZFGongXYangY
But the key word is treatment
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