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amycretin Novo Nordisk, which makes Wegovy and Ozempic, is testing this experimental, unimolecular drug to target two hormone pathways, GLP-1 and amylin, a hormone that helps control hunger

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Given that DPP-4 clearly plays a role in the clearance of a number of hormones involved in the regulation of glucose homeostasis, the question arises of whether changes in DPP-4 activity might play a role in the pathogenesis of T2DM

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Glucagon in disease Hyperglucagonaemia contributes to a variety of diseases Hyperglucagonaemia has been reported in various diseases/conditions including type 2 diabetes, type 1 diabetes, obesity, fatty liver diseases and kidney diseases [22]