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Although long-acting glucagon-like peptide-1 (GLP-1) analogues are now in routine use for diabetes and are now being utilised for obesity per se , the need for ever better treatments has driven the development of co-agonists, with the theoretical advantages of improved efficacy by targeting multiple pathways and reduced adverse effects

In medical weight loss, semaglutide may help appropriate patients by supporting fullness after smaller meals, reducing appetite and food noise, improving portion control, supporting blood sugar regulation, helping some patients improve cardiometabolic risk markers, and supporting weight loss when combined with nutrition, activity, and medical monitoring

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insulin resistance, high cholesterol, high blood pressure, fatty liver, PCOS) 6+ months of structured lifestyle therapy without adequate success Family ready to commit to injections, monitoring & follow-up (labs required before or within 30 days of first visit) Approximate BMI Thresholds 16-year-old boy 27.5+ 16-year-old girl 29+ 17-year-old boy 28.4+ 17-year-old girl 29.5+ Final eligibility is determined after a full medical review