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P., Torrente, L., Falzone, A., Elkins, C

Sustained weight loss after treatment with a glucagon-like peptide-1 receptor agonist in an obese patient with schizophrenia and type 2 diabetes

Studies show that between 40 to 70% of people experience gastrointestinal issues such as nausea, vomiting, diarrhea, constipation, and bloating

1, 2a, 2b and Extended Data Fig

The pharmacokinetic properties including intestinal permeability, first-pass metabolism, microbiota-mediated biotransformation, plasma half-life, and systemic availability is essential for translational relevance

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