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Lenmeldy is the first FDA-approved gene therapy for MLD, which is caused by a deficiency of the arylsulfatase A (ARSA) enzyme, a state that leads to a buildup of fatty substances in the cells
Kwon and Park 2015 reported that intra-articular AOD-9604 injections, especially when combined with hyaluronic acid, improved cartilage scores and reduced lameness in a rabbit collagenase-induced osteoarthritis model
When liver function is compromisedby poor diet, alcohol, medications, or simply agefat accumulates in liver cells (hepatic steatosis)
More than 2 out of 5 users carry buy now, pay later debt and one-quarter of them missed a payment last month, the survey showed
The engineered CAR used the scFv regions previously described 42,54 but with the CD8a hinge/TM domains and 4-1BB costimulatory domain
doi:10.1016/j.clnesp.2018.07.011 Mollazadeh H, Hosseinzadeh H
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