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For patients with bi-allelic mutations in POMC , LEPR , or MC4R [45] , bariatric surgery achieved only limited long-term weight loss, with all patients experiencing significant weight regain after initial weight reduction

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Understanding these variables helps contextualise any changes observed during treatment and prevents unnecessary anxiety

Yue W, Li Y, Ou D, Yang Q

Your provider will help determine which options are right for you based on your symptoms and lab work

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