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When developing medications related to FMT, it is crucial to maximize safety while considering both immediate and long-term adverse effects (265)
A 2009 placebo-controlled pilot study by Ali et al
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The maximum plasma concentrations (C(max)) of adducts for immediate release (IR) and extended release (ER) formulations were 0.108 (0.020) and 0.100 (0.028) nmol/mL serum, respectively, and were two orders of magnitude lower than the maximum APAP adduct levels previously reported in adults with acute liver failure secondary to APAP
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