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AOD-9604 vs GLP-1 S GLP-1 S (semaglutide) works through an entirely different system than AOD-9604: it activates GLP-1 receptors to slow gastric emptying, increase satiety, and improve glycemic control, producing weight loss primarily by reducing food intake rather than by acting on fat cells directly
Researchers study this fragment for its selectivity within adipose tissue signaling pathways independent of IGF-1 receptor activation
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