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Overexpression of GSH and GPx has been linked to resistance in cisplatin and doxorubicin-treated cancers, while Nrf2 activation enhances the antioxidant response, promoting drug resistance [80]
Research interest also encompasses its role as a copper transport peptide and its effects on matrix metalloproteinase expression, extracellular matrix remodeling dynamics, and neurotrophin signaling pathways in in vitro models
MMP-9 expression is up-regulated by macrophages and is responsible for degrading extracellular matrix proteins including collagen, which results in thinning of the plaque's fibrous cap
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Protocol control: researchers can prepare solutions independently per SOP
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And those who stop taking them typically regain two-thirds of the weight they lost within a year
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