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Retatrutide causes significant physiological changes on its own appetite suppression, GI adjustment, metabolic recalibration
10.1111/jgh.16526 103 YangC.LiangL.LvP.LiuL.WangS.WangZ.et al (2021)
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Even in a person with a slower metabolic rate due to hypothyroidism, reducing caloric intake through GLP-1-mediated satiety signals creates the deficit needed for weight loss
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2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults
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