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However, unlike glycolytic and lipogenic pathways, where specific metabolic enzymes such as hexokinase 2 and FAS are known to be deregulated by oncogene(s) or by inactivation of tumor suppressors 16,17 , there is limited evidence for cancer-associated abnormal expression or activity of the enzymes directly involved in the FAO pathway

In Principles of Neuro-Oncology , Cham: Springer International Publishing, 2021

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Tirzepatide also improves liver fat, primarily through weight loss and improved insulin sensitivity