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BUSTER version 2.10.2 Cambridge: Global Phasing Ltd, UK (2016)
Who should consider DSIP DSIP may be appropriate for certain profiles while less suitable for others
22 and 23) where they can be most effective during the initiation and early propagation phases (33, 53)
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The bottom line: Our findings suggest that GLP-1RA and SGLT2i (and especially SGLT2i with the lowest number needed to treat (NNT) for nearly all study outcomes) may be the preferred glucose-lowering agents for cardiovascular risk reduction in patients at moderate risk for CVD, building on and consistent with existing RCT evidence in the high-risk population. This report highlights potential preference for GLP-1 drugs as a first-line treatment for Type 2 diabetes related to its cardioprotective effect
The most likely cause of the renal changes seen after maternal exposure is the inability of the developing fetal kidney to handle the increased urinary volume caused by the SGLT2 inhibitor (71)
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