glp-1 and anesthesia Are Serious Risks of Semaglutide Other Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia GLP-1 medications are increasingly common,

Labarrere and Kassab, 2021

Long-Term Weight Management Strategy: Sustainable weight loss often requires lifestyle changes beyond medication

Sheng B, Gao S, Chen X, Liu Y, Lai N, Dong J, Sun J, Zhou Y, et al

The selectivity data are primarily from Raun et al.'s rat work

Patients with low-normal or borderline B12 (200400 pg/mL) may experience quicker symptom relief and fewer adverse effects than those with truly deficient levels, who may require supplemental or prescription-grade B12 dosing instead

Key Regulatory Points as of 2026: Not FDA-approved for any medical indication Cannot legally be sold as a drug, food, or dietary supplement for human consumption Legally sold as a "research chemical," not intended for human use Not a DEA-scheduled substance, so possession is not illegal (unlike anabolic steroids) Many medical clinics offer BPC-157 treatments despite lack of approval The FDA has expressed safety concerns due to the lack of human clinical trial data and the potential for adverse effects from unregulated manufacturing